Quantification of Glutathione in Plasma Samples by HPLC Using 4-Fluoro-7-nitrobenzofurazan as a Fluorescent Labeling Reagent
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چکیده
منابع مشابه
Determination of taurine in biological samples by high-performance liquid chromatography using 4-fluoro-7-nitrobenzofurazan as a derivatizing agent.
OBJECTIVE A highly sensitive and rapid high-performance liquid chromatography method with pre-column derivatization with 4-fluoro-7-nitrobenzofurazan was developed for determination of taurine in biological samples, including plasma, brain, and liver. METHODS The optimum derivatization reaction temperature was 70 °C, and at this temperature the reaction was complete within 3 min. The derivati...
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The oral dosages formulations from Pothomorphe umbellata (Piperaceae) can only be therapeutically evaluated after establishing 4-nerolidylcatechol (4-NRC) pharmacokinetic profile in plasma. For that purpose, a unique analytical method validation using HPLC-UV detection was developed for analysis of rat plasma samples. The animals received 10 mg/kg b.w. of 4-NRC i.v.. Analytical conditions were ...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2012
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/bmr039